74 research outputs found

    Recreation, tourism and nature in a changing world : proceedings of the fifth international conference on monitoring and management of visitor flows in recreational and protected areas : Wageningen, the Netherlands, May 30-June 3, 2010

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    Proceedings of the fifth international conference on monitoring and management of visitor flows in recreational and protected areas : Wageningen, the Netherlands, May 30-June 3, 201

    Typical tourists : Research into the theoretical and methodological foundations of a typology of tourism and recreation experiences

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    Typical tourists are recognisable from a distance. They appear out of place with their loud coloured outfits, often sunburned, walking around loaded with cameras and video-equipment and studying city maps. Yet, tourists are not always all the same. Adventurous eco-tourists, with hiking boots and a good quality daypack, clearly search for a different experience than middle-aged cultural tourists do. Typologies have been developed to classify different groups of tourists and recreationists. However, problems have arisen since the various approaches are quite different and the classification schemes used 'arbitrary'. The question remains "which typology should have preference"? This book reports a long-term project to establish a theoretical and useful approach to develop a typology of experiences for tourism and recreation. The theoretical framework used as a starting point was Eric Cohen's (1979) phenomenology of tourist experiences. The research covers different activities (camping, sight seeing by car, hiking) and settings (nature areas, bungalow parks, Costa Rica, the Netherlands, Southeast Asia), while maintaining a degree of comparison with the theoretical framework adopted for this study. A detailed insight into the methodological aspects of the approach is provided to enable researchers and students alike to use and build upon the methodology and results. The approach is also meant to be a source of inspiration for policy development and planning for a diversified tourist environmen

    Post-transplantation cutaneous and renal Aspergillus infection

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    A 68-year old renal transplant recipient suffered multiple complications following initial good graft function from a deceased-donor transplant. Late in the first week he was oliguric with haematuria; the graft failed in week 2 following development of a haematoma from rupture of a renal artery aneurysm. He had a recurrent bleed from the internal iliac graft site and subsequently developed painful dark patches on his leg, distal to where the transplant had been. Histology from the explanted graft and skin biopsies demonstrated Aspergillus flavus; this was also grown in culture of the external iliac artery tissue. Systemic aspergillosis is rare but well recognised, especially in the immunocompromised. Presentations include mycotic aneurysms and secondary cutaneous aspergillosis from haematogenous spread. Diagnosis requires confirmation by histology or direct culture, but a high beta-glucan concentration and positive galactomannan antigen can suggest invasive fungal infection in the early stages of the disease. Cases should be managed with systemic antifungals and involvement of local microbiology services; unfortunately, prognosis is poor

    Bosbouw en plattelandsontwikkeling in Europa

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    Typologie van plattelandsontwikkeling en plattelandsvernieuwing, de verschillende visies op de gewenste richting van plattelandsvernieuwing (agri-ruraal; utilitair; hedonistisch), en de rol die bosbouw en vergroting van het bosareaal in Europees verband hierbij kan spele

    Vasopressinergic modulation of stress responses in the central amygdala of the Roman high-avoidance and low-avoidance rat

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    The central nucleus of the amygdala (CEA) is selectively involved in the passive component of the behavioral (immobility) and the accompanying parasympathetic response during conditioned, stressful environmental challenges. Vasopressinergic mechanisms in the brain seem to play a role in these stress responses. The effects of the neuropeptides arginine-8-vasopressin (AVP) and oxytocin (OXT) on modulating CEA activity during conditioned stress of inescapable footshock were studied in male Roman high-avoidance (RHA/Verh) and low-avoidance (RLA/Verh) rats, psychogenetically selected on the basis of shuttle-box acquisition behavior. In RLA/Verh rats, the cardiac and behavioral responses to the conditioned emotional stressor were bradycardia and immobility, suggesting an important role for the CEA in these rats. The RHA/Verh rats, however, failed to show any change in heart rate or immobility in response to a conditioned stress situation. The low dose of AVP (20 pg) in the CEA of conscious RLA/Verh rats caused an enhancement of the stress-induced bradycardiac and immobility response. However, the high dose of AVP (2 ng) and OXT (200 pg) attenuated the bradycardiac and immobility responses in the RLA/Verh rats. Infusion of AVP and OXT in the RHA/Verh rats failed to induce any change in heart rate nr immobility. Binding studies revealed that the AVP receptor selectively binds AVP with high affinity. In contrast, the OXT receptor recognizes both AVP and OXT with a similar (but lower) affinity. This suggests that the behavioral and autonomic responses of the high dose of AVP may be caused by OXT receptor stimulation. In conclusion, on the basis of the present results one may hypothesize that CEA differences in AVP and OXT innervation and/or receptor densities may contribute to the differences in coping strategy found in these animals.

    Biocultural diversity : a novel concept to assess human-nature interrelations, nature conservation and stewardship in cities

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    Biocultural diversity is an evolving perspective for studying the interrelatedness between people and their natural environment, not only in ecoregional hotspots and cultural landscapes, but also in urban green spaces. Developed in the 1990s in order to denote the diversity of life in all its manifestations. biological, cultural and linguistic. co-evolving within complex socio-ecological systems such as cities, biocultural diversity was identified in the GREEN SURGE project as a response to recent challenges cities face. Most important challenges are the loss of nature and degradation of ecosystems in and around cities as well as an alienation of urban residents from and loss of interaction with nature. The notion of biocultural diversity is dynamic in nature and takes local values and practices of relating to biodiversity of different cultural groups as a starting point for sustainable living with biodiversity. The issue is not only how to preserve or restore biocultural practices and values, but also how to modify, adapt and create biocultural diversity in ways that resonate with urban transformations. As future societies will largely diverge from today's societies, the cultural perspective on living with (urban) nature needs careful reconsideration. Biocultural diversity is not conceived as a definite concept providing prescriptions of what to see and study, but as a reflexive and sensitising concept that can be used to assess the different values and knowledge of people that reflect how they live with biodiversity. This short communication paper introduces a conceptual framework for studying the multi-dimensional features of biocultural diversity in cities along the three key dimensions of materialized, lived and stewardship, being departure points from which biocultural diversity can be studied.Peer reviewe

    The governance of urban green spaces in selected EU-cities : Policies, Practices, Actors, Topics

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    In a time of continuing urbanization, there is an increasing focus on developing attractive and healthy urban environments. Green spaces, ranging from woodlands and parks to allotment gardens and green roofs, provide a range of ecosystem services that contribute to better cities (Lovell and Taylor, 2013). The Green Infrastructure and Urban Biodiversity for Sustainable Urban Development and the Green Economy project (GREEN SURGE in brief), funded under the EU’s 7th Framework Programme for research, will identify, develop and test ways of linking green spaces, biodiversity, people and the green economy in order to meet the major urban challenges related to land use conflicts, climate change adaptation, demographic changes and human health and well being. The contents of this report are based on work conducted in Work Package 6, one of the eight Work Packages of GREEN SURGE. Work Package 6 focuses on governance arrangements for urban green spaces. In this report, we discuss the findings of the GREEN SURGE Work Package 6 Tier 1 research on identifying and conceptualising innovative participatory governance arrangements in regards to the management of urban green infrastructure

    Overeating, caloric restriction and breast cancer risk by pathologic subtype: the EPIGEICAM study

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    This study analyzes the association of excessive energy intake and caloric restriction with breast cancer (BC) risk taking into account the individual energy needs of Spanish women. We conducted a multicenter matched case-control study where 973 pairs completed lifestyle and food frequency questionnaires. Expected caloric intake was predicted from a linear regression model in controls, including calories consumed as dependent variable, basal metabolic rate as an offset and physical activity as explanatory. Overeating and caloric restriction were defined taking into account the 99% confidence interval of the predicted value. The association with BC risk, overall and by pathologic subtype, was evaluated using conditional and multinomial logistic regression models. While premenopausal women that consumed few calories (>20% below predicted) had lower BC risk (OR = 0.36; 95% CI = 0.21–0.63), postmenopausal women with an excessive intake (≥40% above predicted) showed an increased risk (OR = 2.81; 95% CI = 1.65–4.79). For every 20% increase in relative (observed/predicted) caloric intake the risk of hormone receptor positive (p-trend < 0.001) and HER2+ (p-trend = 0.015) tumours increased 13%, being this figure 7% for triple negative tumours. While high energy intake increases BC risk, caloric restriction could be protective. Moderate caloric restriction, in combination with regular physical activity, could be a good strategy for BC prevention

    Regulation of Intestinal Immune Response by Selective Removal of the Anterior, Posterior, or Entire Pituitary Gland in Trichinella spiralis Infected Golden Hamsters

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    The influence of anterior pituitary hormones on the gastrointestinal tract of humans and animals has been previously reported. Hypophysectomy (HYPOX) in the rat causes atrophy of the intestinal mucosa, and reduction of gastric secretion and intestinal absorption, as well as increased susceptibility to bacterial and viral infections. However, to our knowledge, no findings have been published concerning the immune response following HYPOX during worm infection, particularly that which is caused by the nematode Trichinella spiralis. The aim of this work was to analyze the effects of total or partial HYPOX on colonization of T. spiralis in the intestinal lumen, together with duodenal and splenic cytokine expression. Our results indicate that 5 days post infection, only neurointermediate pituitary lobectomy (NIL) reduces the number of intestinally recovered T. spiralis larvae. Using semiquantitative inmunofluorescent laser confocal microscopy, we observed that the mean intensity of all tested Th1 cytokines was markedly diminished, even in the duodenum of infected controls. In contrast, a high level of expression of these cytokines was noted in the NIL infected hamsters. Likewise, a significant decrease in the fluorescence intensity of Th2 cytokines (with the exception of IL-4) was apparent in the duodenum of control and sham infected hamsters, compared to animals with NIL surgeries, which showed an increase in the expression of IL-5 and IL-13. Histology of duodenal mucosa from NIL hamsters showed an exacerbated inflammatory infiltrate located along the lamina propria, which was related to the presence of the parasite. We conclude that hormones from each pituitary lobe affect the gastrointestinal immune responses to T. spiralis through various mechanisms
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